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Why is this medication prescribed?

Deflazacort is used to treat Duchenne muscular dystrophy (DMD; a progressive disease in which the muscles do not function properly) in adults and children 5 years of age and older. Deflazacort is in a class of medications called corticosteroids. It works by reducing inflammation (swelling) and by changing the way the immune system works.

How should this medicine be used?

Deflazacort comes as a tablet and a suspension (liquid) to take by mouth. It is usually taken once a day with or without food. Take deflazacort at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take deflazacort exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

If you cannot swallow the tablet whole, you may crush the tablet and mix with applesauce. The mixture should be taken immediately.

Shake the suspension well before each use to mix the medication evenly. Use the measuring device to measure the dose of deflazacort and slowly add the dose to 3 to 4 ounces (90 to 120 mL) of milk or fruit juice and take immediately. Do not mix deflazacort suspension with grapefruit juice.

Your doctor may need to change your dose of deflazacort if you experience unusual stress on your body such as surgery, illness, or infection. Tell your doctor if your symptoms improve or get worse or if you get sick or have any changes in your health during your treatment.

Do not stop taking deflazacort without talking to your doctor. Stopping the drug abruptly may cause symptoms such as loss of appetite, an upset stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss. Your doctor will probably decrease your dose gradually to allow your body to adjust before stopping the drug completely. Watch for these side effects if you are gradually decreasing your dose and after you stop taking the tablets or oral suspension. If these problems occur, call your doctor immediately.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

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